Body Composition in Nutritional Assessment: Bioimpedance Analysis Revisited

Electrical Bioimpedance (EBI) Technology it is currently use for non-invasive assessment of body fluid distribution, The current approaches most often wrong estimate the amount of intracellular fluid (ICF) and therefore the total value for Total Body Water(TBW) and the percentage contribution of the Extracellular Fluid (ECF) to the TBW.

A more accurate and reliable estimation of the ICW would improve the performance of the EBI method for Body Composition Assessment (BCA) and would enable the spreading of the technological approach as reliable and accurate one.

The origin of the wrong estimation is multiple. It might be a result of the multiple simplification applied to obtain a method that it is easy to apply, from limitations of the signal processing methods applied to extract estimators from the EBI measurements, from artifacts present in the EBI measurements and from combination of all of that.

Electrical Bioimpedance (EBI) has the possibility to assess tissue composition of the human body non-invasively. After many years in clinical research use without the expected breakthrough in clinical practice, the basics of its application to nutritional assessment are revisited. New signal processing and analysis approaches of EBI measurements are being tested and validated with the goal of increasing the robustness of the application of EBI for clinical body composition analysis. This investigation includes EBI pre-processing techniques, signal analysis, and validation of estimation approaches.

The overall goal of the project is to improve the performance of EBI measurements for BCA. Intermediate goals are to find the pre-processing and analysis techniques with specific robustness to measurement artifacts. To improve find reliable methods for estimating the amount of ICF.


Research team

MedTech West partner

Fernando Seoane, Ruben Buendia

Clinical partner

Prof. Ingvar Bosaeus, Unit for Clinical Nutrition

Industrial partner

Z-Health Technologies AB