A MedTech West seminar: Functional basis for brain plasticity in reconstructive upper-limb surgery in tetraplegia

Although spinal cord injury (SCI) remains incurable, surgical recon-struction of the arm and hand in tetraplegia is a powerful tool to restore upper extremity functions and personal freedom, e.g. the ability to groom, self-feed, self-catheterize, lift objects, write, swim, maneuver wheel-chair and drive a car. Tendon transfers are the most common procedure in which the distal end of a functionally intact muscle is detached, rerouted and reattached to a nonworking muscle to replace its original function. The concept that the central nervous system needs to relearn movement execution following tendon transfer is not new. However, the neural mechanisms involved are tremendously poorly. Grip reconstruction amounts to a unique, focused stimulus for brain plasticity. The intervention therefore yields a rare opportunity to address the neural mechanisms involved. Recent developments in neuroimaging of the brain have the potential to elucidate plastic mechanisms following tendon transfer. The objective of the present study is to delineate patterns of cortical reorganization following grip reconstruction in tetraplegia patients using both functional magnetic resonance imaging (fMRI) and functional Near Infrared Spectroscopy (fNIRS).

This seminar will be presented by Lina Bunketorp Käll, Ph.D., RPT at the Center for Advanced Reconstruction of Extremities (C.A.R.E), Sahlgrenska University Hospital/ Mölndal.

Very welcome to an interesting seminar on 29 February!

A light lunch will be served after the seminar to those who have registered at the latest on Wednesday 24 February.

Day: 29 February
Time: 11:30-12:30 (13:00 incl. lunch)
Place: Förmaket, Vita stråket 12, Sahlgrenska University Hospital