A MedTech West seminar with professor Helge Malmgren on the clinical aspects of hippocampal function

Since around twenty years, delineation of the hippocampi in MR images has been done in a variety of disorders and other specific conditions, mainly for research purposes but sometimes as part of clinical routine. Hippocampal segmentation and volumetry is performed by many different research groups and with several different techniques, both manual and automatic. In several disorders – not only dementia and pre-dementia – hippocampal volumes have turned out to be lower than normal. This naturally gives rise to some questions, for example:

  • What aspects of hippocampal function do these findings reflect?
  • Do they motivate the use of hippocampal segmentation and volumetry in yet other disorders and conditions?
  • Is it worthwhile to extend segmentation and volumetry to other parts of the medial temporal lobe?
  • To what extent are other MR techniques, e.g. DTI and fMRI, to be regarded as complements to standard segmentation in this region, and to what extent can (and should) they replace it?
  • Since the answer to the first question has implications for all the others, this seminar will focus on it. It has no simple and clear cut answer because the functions of the hippocampus are still very much contested. I will review some facts, some plausible hypotheses and some open questions about hippocampal functioning. The evidence is drawn from four sources: classical ”organic psychiatry” from the 1870s to the 1970s, psychological research from the last half century, neurophysiological research that has also been going on for almost 50 years but has accelerated during the last ten, and finally the segmentation and volumetry literature itself.

    The seminar will be presented by Helge Malmgren, PhD, MD and emeritus professor in theoretical philosophy at the University of Gothenburg.

    Day: Friday 15 April
    Time: 13:00-13:45 (14:15 incl. coffee)
    Place: Förmaket, Vita stråket 12, Sahlgrenska Universitetssjukhuset

    Please, note the time for this seminar. At this seminar, we are serving “fika”. Please, click here to register in Regionkalendern at the latest on Monday 11 April. If you have any questions, email: helene.lindstrom@medtechwest.se.