Master thesis presentation: Development of an experimental pipeline for high-Tc SQUID-based MEG studies of neural oscillations

Development of an experimental pipeline for high-Tc SQUID-based MEG studies of neural oscillations presented by Sowmitri Ramachandran and Sahana Prasanna, master students of Biomedical Engineering at Signals and Systems, Chalmers University of Technology

Supervisor: Justin Schneiderman

Date: Aug 31st, 2015

Time: 10 am.

Place: MedTech West Conference room at Röda stråket 10B, Sahlgrenska University Hospital

Abstract:

Neural oscillations are a class of brain signals that are commonly studied by neuroscience researchers and clinicians. Magnetoencephalography (MEG) is a neuro-imaging technique that is often used in such studies because it combines very high temporal resolution (< 1 ms) with moderate spatial resolution (< 1 cm). Our group is working to develop high critical-temperature superconducting quantum interference devices (high-Tc SQUIDs) for MEG applications because they promise, e.g., improved sensitivity to brain activity as compared to the state-of-the art. A robust and well-tested experimental pipeline is paramount to demonstrating this advantage. We have developed such a pipeline that accounts for the specificities of high-Tc SQUID-based MEG and tested it with experimental recordings of neural oscillations in human subjects. This pipeline can be used for further demonstrations of the benefit of performing MEG with high-Tc SQUID technology, both for neuroscience research and clinical applications.