MedTech West seminar – Measuring Tissue Water Diffusion with MRI: Reconciling Models with Reality

By any account, magnetic resonance (MR) diffusion imaging has proved a very successful imaging approach. The ability to diagnose stroke-related damages early and to characterize and monitor tumor lesions, along with the ability to capture fiber architecture, has made it an especially valuable diagnostic and research tool. The development of reliable diffusion imaging techniques, capable of probing slow random motion in the presence of involuntary rigid motion and tissue deformation, turned out to be a major challenge.

A brief survey of various approaches, including novel methods that promise rapid, more detailed probing of complex diffusion with improved geometric fidelity, is provided in this presentation. Tissue water diffusion values measured in clinical routine exams are now widely used for tissue characterization. There is, however, only a limited understanding how the tissue environment at the cellular level influences the observed diffusion parameters.

As will be shown in this presentation, measurements of simple diffusion environments can further our understanding about the complex diffusion in tissues. These findings can be reduced into simple models that permit a purely mathematical description of the measurement. As in many other research areas, several models tend to agree well with the measurements made, but ultimately only one agrees with reality.

The seminar will be presented by Professor Stephan Maier, Department of Radiology, Sahlgrenska University Hospital.

 

Date: April 24, 2014
Time: 11:30-12:15 (-13:00 incl lunch)
Location: Kammaren, Vita Stråket 12, Sahlgrenska University Hospital

Register by sending an email to seminars@medtechwest.se. A light lunch will be served at the venue to registered participants.
Please write “MTW seminar Apr 24” in the subject line. Last day for registration is April 22.